Categoria
Methylprednisolonum [Inn-Latin]
Marchi,
Methylprednisolonum [Inn-Latin]
Analoghi
Methylprednisolonum [Inn-Latin]
Marchi miscela
Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate) Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur) Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water) Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate) Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)
Methylprednisolonum [Inn-Latin]
Formula chimica
C22H30O5
Methylprednisolonum [Inn-Latin]
RX link
http://www.rxlist.com/cgi/generic/methprd.htm
Methylprednisolonum [Inn-Latin]
FDA foglio
Methylprednisolonum [Inn-Latin]
DMS (foglio di materiale di sicurezza)
Methylprednisolonum [Inn-Latin]
Sintesi di riferimento
Sebek, Spero, US Pat. 2,897,218 (1959)
Methylprednisolonum [Inn-Latin]
Peso molecolare
374.471 g/mol
Methylprednisolonum [Inn-Latin]
Temperatura di fusione
232.5 oC
Methylprednisolonum [Inn-Latin]
H2O Solubilita
120 mg / L
Methylprednisolonum [Inn-Latin]
Stato
Solid
Methylprednisolonum [Inn-Latin]
LogP
2.134
Methylprednisolonum [Inn-Latin]
Forme di dosaggio
Compresse; sospensione
Methylprednisolonum [Inn-Latin]
Indicazione
Terapia aggiuntiva per la somministrazione a breve termine nell'artrite reumatoide.
Methylprednisolonum [Inn-Latin]
Farmacologia
Metilprednisolone e suoi derivati, metilprednisolone sodio succinato e acetato di metilprednisolone, glucocorticoidi sintetici sono utilizzati come farmaci antinfiammatori o immunosoppressivi.
Methylprednisolonum [Inn-Latin]
Assorbimento
Biodisponibilità orale 80-99%
Methylprednisolonum [Inn-Latin]
Tossicita
LD50 = 2000 mg / kg (per via orale nel ratto)
Methylprednisolonum [Inn-Latin]
Informazioni paziente
Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or
measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.
Methylprednisolonum [Inn-Latin]
Atto interessato organismi
Gli esseri umani e altri mammiferi